ABSTRACT
Objective:
Coronary artery ectasia (CAE) is a cardiovascular disease characterized by dilatation of the coronary arteries and microvascular coronary ischemia. P-wave peak time duration (PWPT), T wave peak to end (Tp-Te) interval and Tp-Te/QS ratio are electrocardiographic (ECG) repolarization parameters associated with an increased risk of arrhythmia. Although awareness of CAE has increased in recent years, there is a paucity of available data on its arrhythmogenic effects. This study aims to evaluate the relationship between CAE and repolarization parameters as PWPT, Tp-Te interval and Tp-Te/QS ratio.
Material and Methods:
Retrospective data analysis of 45 patients with CAE and 51 control patients with normal coronary anatomy was performed. Clinical data, electrocardiogram results and coronary angiography results were analyzed. Among ECG parameters, PWPT, Tp-Te interval and Tp-Te/QTc ratios were particularly emphasized.
Results:
In the comparison between the CAE group and the control group, Tp-Te and Tp-Te/QTc ratios were significantly higher in CAE patients (p=0.013 and p=0.008, respectively). However, no significant difference was found in the PWPT range (p=0.289).
Conclusion:
This study reveals the existence of an association with ECG parameters reflecting myocardial repolarization in CAE patients. Especially increased Tp-Te and Tp-Te/QTc ratios indicate that the risk of ventricular arrhythmogenicity may be increased in CAE patients. The results emphasize the clinical importance of electrocardiogram investigations in patients with CAE.