Abstract
Objective
Acute coronary syndromes (ACS) refer to a group of diseases in which the blood flow to the heart is reduced as a result of the involvement of the epicardial coronary vessels. Accurate assessment of prognostic risk and investigation of the factors contributing to atherosclerosis are considered critical strategies to improve patient outcomes. Determination of the prognostic value of advanced lung cancer inflammation index (ALI) in ACS.
Material and Methods
A total of 3129 ACS patients, including 1451 with ST elevation myocardial infarction (STEMI) and 1678 with non-ST elevation myocardial infarction (NSTEMI), diagnosed between 2020 and 2024, were included in the study. ALI were calculated in all patients and the two groups were compared. Multiple logistic regression analysis was used to determine the predictors. P<0.05 values were considered statistically significant.
Results
The findings of this study showed that ALI [odds ratio (OR) =2.106; 95% CI: 1.431-2.282; P<0.001), neutrophil-lymphocyte ratio (NLR) (OR = 1.231; 95% confidence interval (CI): 0.971-1.411; P<0.001), diabetes mellitus (DM) (OR =1.389; 95% CI: 0.952-1.723; P=0.008), troponin value (OR =1.531; 95% CI: 1.108-1.907; P=0.030), body mass index (BMI) (OR = 1.132; 95% CI: 0.941-1.321; P=0.023) and neutrophil count (OR =1.093; 95% CI: 0.641-1.323; P=0.028) are independent potential predictors of myocardial infarction.
Conclusion
In conclusion, we determined that ALI, NLR, DM, troponin value, BMI, and neutrophil count are an independent potential predictor in NSTEMI and STEMI patients.
Keywords: Advanced lung cancer inflammation index, neutrophil-to-lymphocyte ratio, body mass index, acute coronary syndrome
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